Monday, December 28, 2015

New direction for stent technology now in India

What has made angio plasty and stenting comparable to bypass surgery? It's less invasive, allows quicker recovery and provides efficacious patient outcomes. However, reoccurrence at the site of block treated with angioplasty can be attributed to three factors Proliferation of cells on the inner lining of vessels.Elastic recoil of vessels.

Artery gets narrowed (negative remodeling).

Stents can take care of negative remodeling and elastic recoil by its scaffolding property. Stent is basically a hollow metallic tube mounted on a balloon and deployed at the site of blockage and made adherent to the vessel wall by high pressure balloon. This makes sure the stent is perfectly and adequately in contact with the vessel wall. The balloon is then deflated and removed.
The current generation Drug Eluting Stents (DES) are coated with drugs that inhibit the growth of cells within the vessel wall. With DES, all the above mentioned three issues are taken care of.Unfortunately , some DES may lead to late blood clotting within the stent, which in turn can be life threatening. Clinical data has shown that this issue could be attributed to the body's adverse reaction to the polymer. Polymer is a substance used on the surface of the stent to hold the drug and enable its release gradually . An allergic reaction to this poly mer is a potential source for clotting of the stent.
The new generation SYNERGY stent is the only FDA approved clinically proven solution available to this hazardous phenomenon. Its PLGA polymer disappears shortly after the drug is fully eluted at three months, leaving behind a bare metal stent (BMS).Moreover, SYNERGY's thin strut design makes it easy to deliver and minimises injury to the vessel wall.
According to Dr Ashwin B Mehta (Director of Cardiology , Jaslok Hospital), “SYNERGY stent reduces the chance of stent clotting significantly and considerably . This will ensure highest standard of patient safety.“
Patients with a stent, who may also need to undergo other non-cardiac surgeries, often face the fear of stent clotting if dual antiplatelet therapy is discontinued in the middle. A SYNERGY stent may obviate the need for using anti-clotting medication in the long run for select patients. This feature along with faster disposal of drugs and polymer from the body, which is now possible with the SYNERGY stent, may pave the way for high standards of patient safety.
(*Procedures given are based on the expert's under standing of the said field)

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